Primary Antibodies
p53 Ab-5 (Clone DO-7) Mouse Monoclonal Antibody
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Overview
Host: Mouse
Clone: DO-7
Isotope: IgG2b/ K
Species Reactivity: Human. Others not known
Epitope: aa37-45
Immunogen: Recombinant human wild type p53 protein expressed in E. coli
Molecular Weight: 53kDa
Positive Control: SKBR-3 or MDA-231 cells. Colon CAs
Localization: Nuclear
Application: IHC, WB, IP
Purification Method: Protein A chromatography
Products
| SKU | Regulatory Status | Format | Volume | Action |
|---|---|---|---|---|
| MS-186-B1: p53 | RUO | Biotinylated with BSA and Azide | 0.5 ml | Request a Quote |
| MS-186-MPABX: p53 | RUO | Purified Ab without BSA and Azide | 1 ml | Request a Quote |
| MS-186-P: p53 | IVD | Purified Ab with BSA and Azide | 1 ml | Request a Quote |
| MS-186-P1: p53 | IVD | Purified Ab with BSA and Azide | 0.5 ml | Request a Quote |
| MS-186-RQ: p53 | IVD | Ready to use | 12 ml | Request a Quote |
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