Primary Antibodies
Sterol Regulatory Element Binding Protein–1 Ab-1 [2A4]
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SREBP-1 and –2 are transcription factors which participate in the control of cholesterol homeostasis. SREBPs proteins, which are attached to the endoplasmic reticulum and nuclear envelope, are proteolytically cleaved and thus activated in response to conditions of low cellular sterol.
Overview
Host: Mouse
Clone: 2A4
Isotope: IgG1/ k
Species Reactivity: Human and Hamster. Others not- known
Epitope: aa 301-407
Immunogen: Recombinant protein encoding N-terminal amino acid s 301-407 (the bHLH/leucine zipper domain ) of human SREBP-1
Molecular Weight: 125kDa (precursor) and 60-70kDa (cleaved )
Positive Control: HeLa and IMR5 cells
Localization: Cytoplasmic and nuclear
Application: WB
Purification Method: Protein G chromatography
Pricing
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