Primary Antibodies
CD36 / GPIIIb / GPIV Ab-3 (Clone 185-1G2)
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CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria.
Overview
Host: Mouse
Clone: 185-1G2
Isotope: IgG2a/ k
Species Reactivity: 220-240kDa
Epitope: Not determined
Immunogen: Stimulated human leukocytes
Molecular Weight: 88kDa
Positive Control: Tonsil
Localization: Cell Membrane
Application: IF, FC
Purification Method: Protein A chromatography
Pricing
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