Primary Antibodies

c-erbB-3 / HER-3 Ab-2 (Clone 2F12) Mouse Monoclonal Antibody

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.

Overview

Host: Mouse

Clone: 2F12

Isotope: IgG2a/ k

Species Reactivity: Human, Cow, Rat, and Mouse. Others not known

Epitope: aa1295-1323

Immunogen: Recombinant rat c-erbB-3/HER-3 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D cells

Localization: Cytoplasmic and cell membrane

Application: WB

Purification Method: Protein A chromatography

Products

SKU Regulatory Status Format Volume Action
MS-201-P: c-erbB-3/ HER-3 RUO Purified Ab with BSA and Azide 1 ml Request a Quote
MS-201-P1: c-erbB-3/ HER-3 RUO Purified Ab with BSA and Azide 0.5 ml Request a Quote

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