Primary Antibodies
Epidermal Growth Factor Receptor (EGFR) Ab-10 (Clone 111.6)
EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Overview
Host: Mouse
Clone: 111.6
Isotope: IgG1
Species Reactivity: Human. Not mouse and rat
Epitope: Extracellular domain
Immunogen: Extracellular domain of human recombinant EGFR protein
Molecular Weight: 170kDa (wild type) and 145kDa (vIII variant)
Positive Control: A431 cells. Skin, placenta or squamous cell carcinoma
Localization: Cell membrane
Application: IHC, IP
Purification Method: Protein G chromatography
Products
| SKU | Regulatory Status | Format | Volume | Action |
|---|---|---|---|---|
| MS-378-B1: EGFR | RUO | Biotinylated with BSA and Azide | 0.5 ml | Request a Quote |
| MS-378-P1: EFGR | RUO | Purified Ab with BSA and Azide | 0.5 ml | Request a Quote |
Pricing
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