Primary Antibodies
Epidermal Growth Factor Receptor (EGFR) Ab-2 (Clone 225)
EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Overview
Host: Mouse
Clone: 225
Isotope: IgG1
Species Reactivity: Human, Chimpanzee and Monkey. Does not react with mouse & rat. Others-not known
Epitope: Extracellular domain
Immunogen: Purified EGFR from A431 cells
Molecular Weight: 170kDa (wild type) and 145kDa (vIII variant)
Positive Control: A431 cells
Localization: Cell membrane
Application: IP
Purification Method: Protein G chromatography
Products
| SKU | Regulatory Status | Format | Volume | Action |
|---|---|---|---|---|
| MS-269-P1: EGFR | RUO | Purified Ab with BSA and Azide | 0.5 ml | Request a Quote |
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