Primary Antibodies
p21WAF1 Ab-11 [Clone CP74]
p 21W AF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen ) and blocks DNA replication but not the DNA repair process.
Overview
Host: Mouse
Clone: CP74
Isotope: IgG2b
Species Reactivity: Human. Others not known
Epitope: aa 1-80
Immunogen: Full length human recombinant p21 protein
Molecular Weight: 21kDa
Positive Control: Raji, PC12 cells, Colon carcinoma
Localization: Nuclear
Application: IHC, WB, IP
Purification Method: Protein A chromatography
Products
| SKU | Regulatory Status | Format | Volume | Action |
|---|---|---|---|---|
| MS-891-P0: p21 | RUO | Purified Ab with BSA and Azide | 0.1 ml | Request a Quote |
| MS-891-PABX: p21 | RUO | Purified Ab without BSA and Azide | 0.2 ml | Request a Quote |
Pricing
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