Primary Antibodies
TIMP-2 Ab-5 (Clone 3A4)
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Overview
Host: Mouse
Clone: 3A4
Isotope: IgG2a/ k
Species Reactivity: Human , Mouse, Rat, Rabbit, Cow, and Guinea pig . Others - not known
Epitope: N-terminal
Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein
Molecular Weight: 21kDa
Positive Control: Conditioned, serum-free medium from (TPA-treated ) HFL-1 cells. Pancreatic or colon carcinoma
Localization: Cytoplasmic
Application: IHC, WB, IP
Purification Method: Protein A chromatography
Products
| SKU | Regulatory Status | Format | Volume | Action |
|---|---|---|---|---|
| MS-1485-P: TIMP2 | RUO | Purified Ab with BSA and Azide | 1 ml | Request a Quote |
| MS-1485-P1: TIMP2 | RUO | Purified Ab with BSA and Azide | 0.5 ml | Request a Quote |
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