Primary Antibodies

Troponin T, Cardiac Isoform Ab-1 (Clone 13-11)

Troponin T is a thin filament regulatory protein of striated muscle that binds to troponin C and I and to tropomyosin and is required for calcium-dependent ATPase activity of myofibrillar proteins. It is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. This expression in the human heart is affected by heart failure.

Overview

Host: Mouse

Clone: 13-11

Isotope: IgG1

Species Reactivity: Human, Pig, Dog, Rabbit, Rat, Mouse, Guinea pig, Chicken, Sparrow, Goldfish. Does not react with frog

Epitope: FMPNLVPPKI (5’ region of the cardiac gene exon 10)

Immunogen: Purified rabbit cardiac troponin T isoform (TnT4R)

Positive Control: Cardiac muscle

Localization: Mostly over the I bands in myofibrils

Application: IHC, IF

Purification Method: Protein G chromatography

Products

SKU Regulatory Status Format Volume Action
MS-295-P: Troponin T IVD Purified Ab with BSA and Azide 1 ml Request a Quote
MS-295-P1: Troponin T IVD Purified Ab with BSA and Azide 0.5 ml Request a Quote

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