Primary Antibodies
Troponin T, Cardiac Isoform Ab-1 (Clone 13-11)
Troponin T is a thin filament regulatory protein of striated muscle that binds to troponin C and I and to tropomyosin and is required for calcium-dependent ATPase activity of myofibrillar proteins. It is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. This expression in the human heart is affected by heart failure.
Overview
Host: Mouse
Clone: 13-11
Isotope: IgG1
Species Reactivity: Human, Pig, Dog, Rabbit, Rat, Mouse, Guinea pig, Chicken, Sparrow, Goldfish. Does not react with frog
Epitope: FMPNLVPPKI (5’ region of the cardiac gene exon 10)
Immunogen: Purified rabbit cardiac troponin T isoform (TnT4R)
Positive Control: Cardiac muscle
Localization: Mostly over the I bands in myofibrils
Application: IHC, IF
Purification Method: Protein G chromatography
Products
SKU | Regulatory Status | Format | Volume | Action |
---|---|---|---|---|
MS-295-P: Troponin T | IVD | Purified Ab with BSA and Azide | 1 ml | Request a Quote |
MS-295-P1: Troponin T | IVD | Purified Ab with BSA and Azide | 0.5 ml | Request a Quote |
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